7QAV
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound N-((2-(4-cyclopropylphenyl)thiazol-5-yl)methyl)-2-(trifluoromethyl)pyridin-4-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Multiple virulence factor regulator MvfR | polymer | 332 | 37256.5 | 2 | UniProt (Q9I4X0) Pfam (PF00126) Pfam (PF03466) In PDB | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | Transcriptional regulator MvfR |
| 2 | A, B | ~{N}-[[2-(4-cyclopropylphenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine | non-polymer | 375.4 | 2 | Chemie (XBH) | |||
| 3 | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 332 (UniProt: Q9I4X0)
| PDB | External Database | Details |
|---|---|---|
| Gln 294 | Glu 294 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74513.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 750.8 | |
| All* | Total formula weight | 75263.8 |
