7Q9F

Beta-50 fab in complex with SARS-CoV-2 beta-Spike glycoprotein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Spike glycoprotein	polymer	1285	141994.0	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	L, F, K	Beta-50 light chain	polymer	217	23792.4	3		Homo sapiens
3	H, E, J	Beta-50 heavy chain	polymer	223	23769.7	3		Homo sapiens
4	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
5	G, I, M, N, O...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	14	In PDB GlyTouCan (G42666HT)
6	P, V	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	2	In PDB GlyTouCan (G32152BH)
7	A, B, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	25	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 1205 (UniProt: P0DTC2)

PDB	External Database	Details
Phe 18	Leu 18	variant
Ala 80	Asp 80	variant
Gly 215	Asp 215	variant
-	Leu 242	deletion
-	Ala 243	deletion
-	Leu 244	deletion
Ile 243	Arg 246	variant
Asn 414	Lys 417	variant
Lys 481	Glu 484	variant
Tyr 498	Asn 501	variant
Gly 611	Asp 614	variant
Gly 679	Arg 682	conflict
Ser 680	Arg 683	conflict
Ser 682	Arg 685	conflict
Val 698	Ala 701	variant
Pro 983	Lys 986	conflict
Pro 984	Val 987	conflict
Gly 1206	-	expression tag
Ser 1207	-	expression tag
Gly 1208	-	expression tag
Tyr 1209	-	expression tag
Ile 1210	-	expression tag
Pro 1211	-	expression tag
Glu 1212	-	expression tag
Ala 1213	-	expression tag
Pro 1214	-	expression tag
Arg 1215	-	expression tag
Asp 1216	-	expression tag
Gly 1217	-	expression tag
Gln 1218	-	expression tag
Ala 1219	-	expression tag
Tyr 1220	-	expression tag
Val 1221	-	expression tag
Arg 1222	-	expression tag
Lys 1223	-	expression tag
Asp 1224	-	expression tag
Gly 1225	-	expression tag
Glu 1226	-	expression tag
Trp 1227	-	expression tag
Val 1228	-	expression tag
Leu 1229	-	expression tag
Leu 1230	-	expression tag
Ser 1231	-	expression tag
Thr 1232	-	expression tag
Phe 1233	-	expression tag
Leu 1234	-	expression tag
Gly 1235	-	expression tag
Arg 1236	-	expression tag
Ser 1237	-	expression tag
Leu 1238	-	expression tag
Glu 1239	-	expression tag
Val 1240	-	expression tag
Leu 1241	-	expression tag
Phe 1242	-	expression tag
Gln 1243	-	expression tag
Gly 1244	-	expression tag
Pro 1245	-	expression tag
Gly 1246	-	expression tag
His 1247	-	expression tag
His 1248	-	expression tag
His 1249	-	expression tag
His 1250	-	expression tag
His 1251	-	expression tag
His 1252	-	expression tag
His 1253	-	expression tag
His 1254	-	expression tag
Gly 1255	-	expression tag
Ser 1256	-	expression tag
Ala 1257	-	expression tag
Trp 1258	-	expression tag
Ser 1259	-	expression tag
His 1260	-	expression tag
Pro 1261	-	expression tag
Gln 1262	-	expression tag
Phe 1263	-	expression tag
Glu 1264	-	expression tag
Lys 1265	-	expression tag
Gly 1266	-	expression tag
Gly 1267	-	expression tag
Gly 1268	-	expression tag
Ser 1269	-	expression tag
Gly 1270	-	expression tag
Gly 1271	-	expression tag
Gly 1272	-	expression tag
Ser 1273	-	expression tag
Gly 1274	-	expression tag
Gly 1275	-	expression tag
Ser 1276	-	expression tag
Ala 1277	-	expression tag
Trp 1278	-	expression tag
Ser 1279	-	expression tag
His 1280	-	expression tag
Pro 1281	-	expression tag
Gln 1282	-	expression tag
Phe 1283	-	expression tag
Glu 1284	-	expression tag
Lys 1285	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	568668.4
Branched	Number of molecules	17
	Total formula weight	7977.5
Non-Polymers*	Number of molecules	25
	Total formula weight	5530.2
All*	Total formula weight	582176.1

*Water molecules are not included.