7Q90
Crystal structure of TTBK2 in complex with VNG1.63 (compound 32)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tau-tubulin kinase 2 | polymer | 300 | 34467.7 | 2 | UniProt (Q6IQ55) Pfam (PF00069) | Homo sapiens (Human) | |
| 2 | C, E (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | D, F (A, B) | ~{N}-[4-(4-methoxyphenoxy)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine | non-polymer | 332.4 | 2 | Chemie (9IS) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 789 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 299 (UniProt: Q6IQ55)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Pro 8 | Leu 8 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68935.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 854.7 | |
| All* | Total formula weight | 69790.1 |
