7Q8O
Peptide LLSGKE in complex with human cathepsin V C25S mutant
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AA, BA) | Cathepsin L2 | polymer | 221 | 24021.9 | 2 | UniProt (O60911) Pfam (PF00112) | Homo sapiens (Human) | Cathepsin U,Cathepsin V |
| 2 | C, D (PB, PA) | LLSGKE Peptide | polymer | 6 | 646.8 | 2 | synthetic construct | ||
| 3 | E, G, I (AA, BA) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) PubChem (312) | |||
| 4 | F, H, J (AA, BA) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
| 5 | K, L, M (AA, BA, PA) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
AA, BA: 1 - 221 (UniProt: O60911)
| PDB | External Database | Details |
|---|---|---|
| Ala 25 | Cys 138 | engineered mutation |
| Gln 108 | Asn 221 | engineered mutation |
| Gln 179 | Asn 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 49337.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 460.9 | |
| All* | Total formula weight | 49798.3 |
