7Q8N

Peptide KKYDAFLA in complex with human cathepsin V C25A mutant

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (AA, BA)	Cathepsin L2	polymer	222	24137.0	2	UniProt (O60911) Pfam (PF00112)	Homo sapiens (human)	Cathepsin U,Cathepsin V
2	C, D (PA, PB)	KKYDAFLA Peptide	polymer	10	981.2	2		synthetic construct
3	E, K (AA, BA)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	F, G, H, I (AA, BA)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	4	Chemie (MPD)
5	J (BA)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6	L, M, N (AA, BA, PB)	water	water		18.0	322	Chemie (HOH)

Sequence modifications

AA, BA: 1 - 222 (UniProt: O60911)

PDB	External Database	Details
Ala 26	Cys 138	engineered mutation
Gln 109	Asn 221	engineered mutation
Gln 180	Asn 292	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	50236.4
Non-Polymers*	Number of molecules	7
	Total formula weight	635.7
All*	Total formula weight	50872.1

*Water molecules are not included.