7Q8M
Peptide KPKKKTK in complex with human cathepsin V C25A mutant
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AA, BA) | Cathepsin L2 | polymer | 222 | 24137.0 | 2 | UniProt (O60911) Pfam (PF00112) | Homo sapiens (human) | Cathepsin U,Cathepsin V |
| 2 | C, D (PA, PB) | KPKKKTK Peptide | polymer | 9 | 886.2 | 2 | synthetic construct | ||
| 3 | E, F, L (AA, BA) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
| 4 | G, M, N (AA, BA) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) PubChem (753) | |||
| 5 | H, I, J, K (AA) | trifluoroacetic acid | non-polymer | 114.0 | 4 | Chemie (TFA) PubChem (6422) | |||
| 6 | O, P, Q, R (AA, BA, PA, PB) | water | water | 18.0 | 395 | Chemie (HOH) |
Sequence modifications
AA, BA: 1 - 222 (UniProt: O60911)
| PDB | External Database | Details |
|---|---|---|
| Ala 26 | Cys 138 | engineered mutation |
| Gln 109 | Asn 221 | engineered mutation |
| Gln 180 | Asn 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 50046.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1086.9 | |
| All* | Total formula weight | 51133.3 |
