7Q8M
Peptide KPKKKTK in complex with human cathepsin V C25A mutant
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AA, BA | Cathepsin L2 | polymer | 222 | 24137.0 | 2 | UniProt (O60911) Pfam (PF00112) In PDB | Homo sapiens (human) | Cathepsin U,Cathepsin V |
2 | PA, PB | KPKKKTK Peptide | polymer | 9 | 886.2 | 2 | synthetic construct | ||
3 | AA, BA | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
4 | AA, BA | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | AA | trifluoroacetic acid | non-polymer | 114.0 | 4 | Chemie (TFA) | |||
6 | water | water | 18.0 | 395 | Chemie (HOH) |
Sequence modifications
AA, BA: 1 - 222 (UniProt: O60911)
PDB | External Database | Details |
---|---|---|
Ala 26 | Cys 138 | engineered mutation |
Gln 109 | Asn 221 | engineered mutation |
Gln 180 | Asn 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 50046.4 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1086.9 | |
All* | Total formula weight | 51133.3 |