7Q8H
Peptide EVCKKKK in complex with human cathepsin V C25A mutant
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AA, BA) | Cathepsin L2 | polymer | 221 | 24021.9 | 2 | UniProt (O60911) Pfam (PF00112) | Homo sapiens (Human) | Cathepsin U,Cathepsin V |
| 2 | C, D (PA, PB) | EVCKKKK Peptide | polymer | 9 | 890.2 | 2 | Homo sapiens | ||
| 3 | E, F, H, K, L (AA, BA) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 5 | Chemie (MPD) | |||
| 4 | G (AA) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | I, M (AA, BA) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | J, N, O, P (AA, BA) | trifluoroacetic acid | non-polymer | 114.0 | 4 | Chemie (TFA) | |||
| 7 | Q, R, S, T (AA, BA, PA, PB) | water | water | 18.0 | 420 | Chemie (HOH) |
Sequence modifications
AA, BA: 1 - 221 (UniProt: O60911)
| PDB | External Database | Details |
|---|---|---|
| Ala 25 | Cys 138 | engineered mutation |
| Gln 108 | Asn 221 | engineered mutation |
| Gln 179 | Asn 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 49824.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1266.6 | |
| All* | Total formula weight | 51090.8 |
