7Q8F
Peptide GNYKEAKK in complex with human cathepsin V C25A mutant
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AA, BA) | Cathepsin L2 | polymer | 221 | 24021.9 | 2 | UniProt (O60911) Pfam (PF00112) | Homo sapiens (human) | Cathepsin U,Cathepsin V |
| 2 | C, D (PB, PA) | GNYKEAKK Peptide | polymer | 10 | 964.1 | 2 | synthetic construct | ||
| 3 | E, F, H, I, M... (AA, BA) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 7 | Chemie (MPD) | |||
| 4 | G, P (AA, BA) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | J (AA) | trifluoroacetic acid | non-polymer | 114.0 | 1 | Chemie (TFA) | |||
| 6 | K, L, O, Q, R... (AA, BA) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 7 | V, W, X, Y (AA, BA, PB, PA) | water | water | 18.0 | 429 | Chemie (HOH) |
Sequence modifications
AA, BA: 1 - 221 (UniProt: O60911)
| PDB | External Database | Details |
|---|---|---|
| Ala 25 | Cys 138 | engineered mutation |
| Gln 108 | Asn 221 | engineered mutation |
| Gln 179 | Asn 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 49972.1 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1656.8 | |
| All* | Total formula weight | 51628.9 |
