7Q85
Crystal structure of human STING in complex with MD1193
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Stimulator of interferon genes protein | polymer | 204 | 23189.1 | 1 | UniProt (Q86WV6) Pfam (PF15009) | Homo sapiens (human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | B (A) | 9-[(1R,6R,8R,13E,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,16-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadec-13-en-8-yl]purin-6-amine | non-polymer | 658.4 | 1 | Chemie (98F) | |||
| 3 | C (A) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 140 - 343 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Arg 232 | His 232 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23189.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 658.4 | |
| All* | Total formula weight | 23847.5 |
