7Q6W
Crystal structure of the bromodomain of ATAD2 with triazolopyridazine (cpd 22)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ATPase family AAA domain-containing protein 2 | polymer | 130 | 15453.5 | 1 | UniProt (Q6PL18) Pfam (PF00439) In PDB | Homo sapiens (Human) | AAA nuclear coregulator cancer-associated protein,ANCCA |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | A | (1R,9S)-13-[[3-methyl-8-[(1-methylpiperidin-4-yl)amino]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]carbonyl]-11,13-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4,6-trien-10-one | non-polymer | 460.5 | 1 | Chemie (93L) | |||
| 4 | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
A: 981 - 1108 (UniProt: Q6PL18)
| PDB | External Database | Details |
|---|---|---|
| Ser 979 | - | expression tag |
| Met 980 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15453.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 748.7 | |
| All* | Total formula weight | 16202.2 |
