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7Q6V

Crystal structure of the bromodomain of ATAD2 with triazolopyridine (cpd 14)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AATPase family AAA domain-containing protein 2polymer13015453.51UniProt (Q6PL18)
Pfam (PF00439)
In PDB
Homo sapiens (Human)AAA nuclear coregulator cancer-associated protein,ANCCA
2ASULFATE IONnon-polymer96.13Chemie (SO4)
3A(1R,9S)-13-[(8-azanyl-3-methyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)carbonyl]-11,13-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4,6-trien-10-onenon-polymer362.41Chemie (95O)
4waterwater18.0182Chemie (HOH)
Sequence modifications
A: 981 - 1108 (UniProt: Q6PL18)
PDBExternal DatabaseDetails
Ser 979-expression tag
Met 980-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight15453.5
Non-Polymers*Number of molecules4
Total formula weight650.6
All*Total formula weight16104.1
*Water molecules are not included.

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PDB entries from 2024-10-16

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