7Q6T
Crystal structure of the bromodomain of ATAD2 with AZ13824374
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ATPase family AAA domain-containing protein 2 | polymer | 130 | 15453.5 | 1 | UniProt (Q6PL18) Pfam (PF00439) In PDB | Homo sapiens (Human) | AAA nuclear coregulator cancer-associated protein,ANCCA |
2 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
3 | A | (1R,9S,12R)-13-[[8-[[1-(2-fluoranyl-2-methyl-propyl)piperidin-4-yl]amino]-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]carbonyl]-12-propan-2-yl-11,13-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4,6-trien-10-one | non-polymer | 562.7 | 1 | Chemie (96L) | |||
4 | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A: 981 - 1108 (UniProt: Q6PL18)
PDB | External Database | Details |
---|---|---|
Ser 979 | - | expression tag |
Met 980 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 15453.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 754.8 | |
All* | Total formula weight | 16208.3 |