7Q6J
Crystal structure of the human GDAP1 CMT2 mutant-H123R
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ganglioside-induced differentiation-associated protein 1 | polymer | 280 | 32793.5 | 2 | UniProt (Q8TB36) Pfam (PF13417) Pfam (PF13410) | Homo sapiens (human) | GDAP1 |
| 2 | C, D (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 302 (UniProt: Q8TB36)
| PDB | External Database | Details |
|---|---|---|
| Arg 123 | His 123 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65587.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 212.2 | |
| All* | Total formula weight | 65799.2 |
