7Q5H
Keap1 compound complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Kelch-like ECH-associated protein 1 | polymer | 295 | 32064.9 | 2 | UniProt (Q14145) Pfam (PF01344) In PDB | Homo sapiens (human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
| 2 | A | (3S,5S,8R)-8-[[(2S)-1-ethanoylpyrrolidin-2-yl]carbonylamino]-N,N-dimethyl-3,7,11-tris(oxidanylidene)-10-oxa-3$l^{4}-thia-6-azabicyclo[10.4.0]hexadeca-1(16),12,14-triene-5-carboxamide | non-polymer | 506.6 | 1 | Chemie (92I) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A, B: 321 - 609 (UniProt: Q14145)
| PDB | External Database | Details |
|---|---|---|
| Pro 315 | - | expression tag |
| Arg 316 | - | expression tag |
| Gly 317 | - | expression tag |
| Ser 318 | - | expression tag |
| Ala 319 | - | expression tag |
| Gly 320 | - | expression tag |
| Ala 540 | Glu 540 | conflict |
| Ala 542 | Glu 542 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64129.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 542.0 | |
| All* | Total formula weight | 64671.8 |
