7Q3D

Structure of the human CPLANE complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	WD repeat-containing and planar cell polarity effector protein fritz homolog	polymer	790	89649.3	1	UniProt (O95876) Pfam (PF11768) In PDB	Homo sapiens (Human)	hFRTZ,Bardet-Biedl syndrome 15 protein,WD repeat-containing and planar cell polarity effector protein
2	B	Protein inturned	polymer	964	108150.6	1	UniProt (Q9ULD6) Pfam (PF19031) Pfam (PF19032) Pfam (PF19033) In PDB	Homo sapiens (Human)	Inturned planar cell polarity effector homolog,PDZ domain-containing protein 6
3	C	Protein fuzzy homolog	polymer	418	45721.9	1	UniProt (Q9BT04) Pfam (PF19036) Pfam (PF19037) Pfam (PF19038) In PDB	Homo sapiens (Human)

Sequence modifications

A: 2 - 746 (UniProt: O95876)

PDB	External Database	Details
Met -43	-	initiating methionine
Asp -42	-	expression tag
Ser -41	-	expression tag
Ala -40	-	expression tag
Trp -39	-	expression tag
Ser -38	-	expression tag
His -37	-	expression tag
Pro -36	-	expression tag
Gln -35	-	expression tag
Phe -34	-	expression tag
Glu -33	-	expression tag
Lys -32	-	expression tag
Gly -31	-	expression tag
Gly -30	-	expression tag
Gly -29	-	expression tag
Ser -28	-	expression tag
Gly -27	-	expression tag
Gly -26	-	expression tag
Gly -25	-	expression tag
Ser -24	-	expression tag
Gly -23	-	expression tag
Gly -22	-	expression tag
Ser -21	-	expression tag
Ala -20	-	expression tag
Trp -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
Pro -16	-	expression tag
Gln -15	-	expression tag
Phe -14	-	expression tag
Glu -13	-	expression tag
Lys -12	-	expression tag
Ser -11	-	expression tag
Ala -10	-	expression tag
Val -9	-	expression tag
Asp -8	-	expression tag
Leu -7	-	expression tag
Glu -6	-	expression tag
Val -5	-	expression tag
Leu -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Pro 0	-	expression tag
Gly 1	-	expression tag

B: 2 - 942 (UniProt: Q9ULD6)

PDB	External Database	Details
Met -21	-	initiating methionine
Gly -20	-	expression tag
Ser -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ala -10	-	expression tag
Val -9	-	expression tag
Asp -8	-	expression tag
Leu -7	-	expression tag
Glu -6	-	expression tag
Val -5	-	expression tag
Leu -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Pro 0	-	expression tag
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	243521.9
All*	Total formula weight	243521.9

*Water molecules are not included.