7Q2C

mycolic acid methyltransferase Hma (MmaA4) from Mycobac-terium tuberculosis in complex with ZT260

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hydroxymycolate synthase MmaA4	polymer	318	36521.3	1	UniProt (Q79FX8) Pfam (PF02353)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Mycolic acid methyltransferase,MA-MT,S-adenosylmethionine-dependent methyltransferase,AdoMet-MT,SAM-MT
2	B, C, D (A)	DIMETHYL SULFOXIDE	non-polymer		78.1	3	Chemie (DMS)
3	E, F (A)	6-methyl-2H-chromen-2-one	non-polymer		160.2	2	Chemie (3AV)
4	G (A)	water	water		18.0	138	Chemie (HOH)

Sequence modifications

A: 4 - 301 (UniProt: Q79FX8)

PDB	External Database	Details
Met -16	-	initiating methionine
Gly -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
Tyr -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Ser -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Leu -3	-	expression tag
Val -2	-	expression tag
Pro -1	-	expression tag
Arg 0	-	expression tag
Gly 1	-	expression tag
Ser 2	-	expression tag
His 3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36521.3
Non-Polymers*	Number of molecules	5
	Total formula weight	554.7
All*	Total formula weight	37076.0

*Water molecules are not included.