7Q0H
Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-50 and Beta-54
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Beta-54 Fab heavy chain | polymer | 231 | 24547.5 | 1 | Homo sapiens | ||
| 2 | B (L) | Beta-54 Fab light chain | polymer | 214 | 23264.9 | 1 | Homo sapiens | ||
| 3 | C (B) | Beta-50 Fab light chain | polymer | 217 | 23792.4 | 1 | Homo sapiens | ||
| 4 | D (A) | Beta-50 Fab heavy chain | polymer | 223 | 23769.7 | 1 | Homo sapiens | ||
| 5 | E (E) | Spike protein S1 | polymer | 210 | 23646.6 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 6 | F (C) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G00395TQ) |
Sequence modifications
E: 333 - 526 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met 319 | - | initiating methionine |
| Gly 320 | - | expression tag |
| Cys 321 | - | expression tag |
| Val 322 | - | expression tag |
| Ala 323 | - | expression tag |
| Glu 324 | - | expression tag |
| Thr 325 | - | expression tag |
| Gly 326 | - | expression tag |
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| Asn 417 | Lys 417 | variant |
| Lys 484 | Glu 484 | variant |
| Tyr 501 | Asn 501 | variant |
| Lys 527 | - | expression tag |
| Lys 528 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 119021.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 894.8 | |
| All* | Total formula weight | 119915.9 |
