7PWG

Cryo-EM structure of large subunit of Giardia lamblia ribosome at 2.7 A resolution

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	1	rRNA 28S	polymer	2707	878254.5	1		Giardia lamblia ATCC 50803 (Giardia lamblia)
2	3	rRNA 5S	polymer	120	38671.0	1		Giardia lamblia ATCC 50803 (Giardia lamblia)
3	4	rRNA 5.8S	polymer	139	44972.0	1		Giardia lamblia ATCC 50803 (Giardia lamblia)
4	A	Ribosomal protein L2	polymer	251	27090.5	1	UniProt (E2RTN4) Pfam (PF00181) Pfam (PF03947) In PDB	Giardia lamblia ATCC 50803	Ribosomal protein L8
5	B	Ribosomal protein L3	polymer	379	42715.5	1	UniProt (A8BRZ3) Pfam (PF00297) In PDB	Giardia lamblia ATCC 50803
6	C	Ribosomal protein L4	polymer	316	35048.7	1	UniProt (A8B7H8) Pfam (PF00573) Pfam (PF14374) In PDB	Giardia lamblia ATCC 50803
7	D	Ribosomal protein L5	polymer	297	33961.4	1	UniProt (E2RU47) Pfam (PF17144) Pfam (PF14204) In PDB	Giardia lamblia ATCC 50803
8	F	Ribosomal protein L7	polymer	235	27103.4	1	UniProt (A8BRY6) Pfam (PF00327) In PDB	Giardia lamblia ATCC 50803
9	G	60S ribosomal protein L7a	polymer	225	25427.7	1	UniProt (A8BLL7) Pfam (PF01248) In PDB	Giardia lamblia ATCC 50803
10	H	Ribosomal protein L6	polymer	185	20889.4	1	UniProt (A8BNT5) Pfam (PF00347) In PDB	Giardia lamblia ATCC 50803	Ribosomal protein L9
11	I	Ribosomal protein L10	polymer	210	24283.2	1	UniProt (A8BM86) Pfam (PF00252) In PDB	Giardia lamblia ATCC 50803
12	J	Ribosomal protein L11	polymer	173	19767.7	1	UniProt (A8BI95) Pfam (PF00281) Pfam (PF00673) In PDB	Giardia lamblia ATCC 50803
13	L	60S ribosomal protein L13	polymer	234	26640.3	1	UniProt (A8B6M8) Pfam (PF01294) In PDB	Giardia lamblia ATCC 50803
14	M	Ribosomal protein L14	polymer	131	14785.5	1	UniProt (A8B4F8) Pfam (PF01929) In PDB	Giardia lamblia ATCC 50803
15	N	Ribosomal protein L15	polymer	204	24353.7	1	UniProt (A8B8Z6) Pfam (PF00827) In PDB	Giardia lamblia ATCC 50803
16	O	Ribosomal protein L13a	polymer	197	22921.9	1	UniProt (A8BU75) Pfam (PF00572) In PDB	Giardia lamblia ATCC 50803
17	P	Ribosomal protein L17	polymer	164	18722.8	1	UniProt (A8BE76) Pfam (PF00237) In PDB	Giardia lamblia ATCC 50803
18	Q	Ribosomal protein L18	polymer	179	20207.8	1	UniProt (A8B4T7) Pfam (PF17135) In PDB	Giardia lamblia ATCC 50803
19	R	Ribosomal protein L19	polymer	196	23199.2	1	UniProt (A8BH61) Pfam (PF01280) In PDB	Giardia lamblia ATCC 50803
20	S	60S ribosomal protein L18a	polymer	173	20624.9	1	UniProt (A8BT04) Pfam (PF01775) In PDB	Giardia lamblia ATCC 50803
21	T	Ribosomal protein L21	polymer	159	18296.4	1	UniProt (A8B2Q4) Pfam (PF01157) In PDB	Giardia lamblia ATCC 50803
22	U	Ribosomal protein eL22	polymer	171	19942.4	1	UniProt (A8BW84) Pfam (PF01776) In PDB	Giardia lamblia ATCC 50803
23	V	Ribosomal protein L23	polymer	142	15450.0	1	UniProt (A8BS37) Pfam (PF00238) In PDB	Giardia lamblia ATCC 50803
24	X	Ribosomal protein L23A	polymer	141	16053.9	1	UniProt (A8BMP6) Pfam (PF03939) Pfam (PF00276) In PDB	Giardia lamblia ATCC 50803
25	Y	Ribosomal protein L26	polymer	135	15621.4	1	UniProt (A8BFT3) Pfam (PF16906) In PDB	Giardia lamblia ATCC 50803
26	Z	60S ribosomal protein L27	polymer	135	15374.9	1	UniProt (A8B1T3) Pfam (PF00467) Pfam (PF01777) In PDB	Giardia lamblia ATCC 50803
27	a	Ribosomal protein L27a	polymer	149	17167.0	1	UniProt (A8BZ78) Pfam (PF00828) In PDB	Giardia lamblia ATCC 50803
28	b	60S ribosomal protein L29	polymer	62	7363.6	1	UniProt (A8BYY2) Pfam (PF01779) In PDB	Giardia lamblia ATCC 50803
29	c	Ribosomal protein L30	polymer	109	11698.6	1	UniProt (A8B5N7) Pfam (PF01248) In PDB	Giardia lamblia ATCC 50803
30	d	Ribosomal protein L31B	polymer	106	12184.1	1	UniProt (A8BMP3) Pfam (PF01198) In PDB	Giardia lamblia ATCC 50803	Ribosomal protein L31e
31	e	Ribosomal protein L32	polymer	136	15986.0	1	UniProt (A8BMD9) Pfam (PF01655) In PDB	Giardia lamblia ATCC 50803
32	f	Ribosomal protein L35a	polymer	123	13913.1	1	UniProt (A8BKK5) Pfam (PF01247) In PDB	Giardia lamblia ATCC 50803
33	g	Ribosomal protein L34	polymer	120	13528.8	1	UniProt (A8BMF7) Pfam (PF01199) In PDB	Giardia lamblia ATCC 50803
34	h	Ribosomal protein L29	polymer	124	14292.2	1	UniProt (A0A644FBK5) Pfam (PF00831) In PDB	Giardia lamblia ATCC 50803
35	i	Ribosomal protein L36-1	polymer	90	10586.7	1	UniProt (A8BYA6) Pfam (PF01158) In PDB	Giardia lamblia ATCC 50803	Ribosomal protein L36e
36	j	Ribosomal protein L37	polymer	89	10329.0	1	UniProt (A8BLV7) Pfam (PF01907) In PDB	Giardia lamblia ATCC 50803
37	k	Ribosomal L38e	polymer	77	8605.1	1	UniProt (A8B481) Pfam (PF01781) In PDB	Giardia lamblia ATCC 50803
38	l	Ribosomal protein L39	polymer	51	6353.7	1	UniProt (A0A644EZB9) Pfam (PF00832) In PDB	Giardia lamblia ATCC 50803
39	m	Ubiquitin/Ribosomal protein L40e	polymer	127	14343.7	1	UniProt (A8BXE1) Pfam (PF00240) Pfam (PF01020) In PDB	Giardia lamblia ATCC 50803	Ubiquitin/ribosomal protein CEP52
40	o	Ribosomal protein L44	polymer	106	12311.7	1	UniProt (A8BQU8) Pfam (PF00935) In PDB	Giardia lamblia ATCC 50803
41	p	Ribosomal protein L37a	polymer	94	10508.4	1	UniProt (A8BN26) Pfam (PF01780) In PDB	Giardia lamblia ATCC 50803
42	w	E-site tRNA	polymer	76	24500.6	1		Giardia lamblia ATCC 50803 (Giardia lamblia)
43	W	Ribosomal protein L24A	polymer	102	12005.2	1	UniProt (A8BRH7) Pfam (PF01246) In PDB	Giardia lamblia ATCC 50803
44	E	P-site tRNA	polymer	3	894.6	1		Giardia lamblia ATCC 50803 (Giardia lamblia)
45	1, 4, C, F, I...	MAGNESIUM ION	non-polymer		24.3	112	Chemie (MG)
46	1, A, B, C, I...	POTASSIUM ION	non-polymer		39.1	181	Chemie (K)
47	1	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
48		water	water		18.0	4397	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	44
	Total formula weight	1706952.1
Non-Polymers*	Number of molecules	294
	Total formula weight	9949.1
All*	Total formula weight	1716901.2

*Water molecules are not included.