7PW2
Crystal structure of the Abl SH3 domain V73E-A74S-S75R-G76T-D77E mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Non-specific protein-tyrosine kinase | polymer | 60 | 6721.4 | 1 | UniProt (A9UF07) Pfam (PF00018) UniProt (by SIFTS) (P00519) | Homo sapiens (Human) | |
| 2 | B (A) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A: 63 - 120 (UniProt: A9UF07)
| PDB | External Database | Details |
|---|---|---|
| Gly 61 | - | expression tag |
| Gly 62 | - | expression tag |
| Glu 73 | Val 733 | engineered mutation |
| Ser 74 | Ala 734 | engineered mutation |
| Arg 75 | Ser 735 | engineered mutation |
| Thr 76 | Gly 736 | engineered mutation |
| Glu 77 | Asp 737 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 6721.4 | |
| All* | Total formula weight | 6721.4 |
