7PVZ
Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform 2 of Proto-oncogene tyrosine-protein kinase Src | polymer | 61 | 6646.2 | 2 | UniProt (P00523) Pfam (PF00018) | Gallus gallus (Chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | C (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B: 81 - 141 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Val 93 | Glu 93 | engineered mutation |
| Ala 94 | Ser 94 | engineered mutation |
| Ser 95 | Arg 95 | engineered mutation |
| Gly 96 | Thr 96 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13292.4 | |
| All* | Total formula weight | 13292.4 |
