7PVT
Crystal structure of the v-Src SH3 domain Q128R mutant in complex with the synthetic peptide VSL12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tyrosine-protein kinase transforming protein Src | polymer | 61 | 6861.5 | 2 | UniProt (P63185) Pfam (PF00018) | Rous sarcoma virus (strain Schmidt-Ruppin E) (RSV-SR-E) | pp60v-src,p60-Src,v-Src |
| 2 | B, D (B, D) | VSL12 | polymer | 12 | 1317.6 | 2 | unidentified | ||
| 3 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | F (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A, C: 81 - 141 (UniProt: P63185)
| PDB | External Database | Details |
|---|---|---|
| Arg 128 | Gln 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 16358.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 198.2 | |
| All* | Total formula weight | 16556.4 |
