7PVJ
Crystal structure of Thioredoxin Reductase from Brugia Malayi in complex with auranofin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutaredoxin domain-containing protein | polymer | 598 | 66086.8 | 3 | UniProt (A0A0J9XPH7) UniProt (by SIFTS) (A0A1I9G0T9) | Brugia malayi (Filarial nematode worm) | BMA-TRXR-1, isoform d |
| 2 | D, I, N (A, B, C) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 3 | Chemie (FAD) | |||
| 3 | E (A) | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATR) | |||
| 4 | F, G, K, L, M (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 5 | Chemie (MPD) | |||
| 5 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | J (B) | GOLD ION | non-polymer | 197.0 | 1 | Chemie (AU) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 198260.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3674.7 | |
| All* | Total formula weight | 201935.0 |
