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7PV1

Crystal structure of the dimeric mitofilin domain of Mic60 in complex with the CHCH domain of Mic19

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
MICOS complex subunit MIC60 fused to MIC19polymer14917080.34UniProt (G0SHY5)
UniProt (G0S140)
Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)Mitofilin,Mitofilin
2E, F, G
(A, B, D)
TETRAETHYLENE GLYCOLnon-polymer194.23Chemie (PG4)
3H, I, J
(A, B, C)
waterwater18.08Chemie (HOH)
Sequence modifications
A, B, C, D: 3 - 24 (UniProt: G0SHY5)
PDBExternal DatabaseDetails
Gly 1-expression tag
Pro 2-expression tag
A, B, C, D: 27 - 96 (UniProt: G0SHY5)
PDBExternal DatabaseDetails
Gly 25-linker
Ser 26-linker
Gly 97-linker
Ser 98-linker
Gly 99-linker
Ser 100-linker
A, B, C, D: 101 - 149 (UniProt: G0S140)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight68321.3
Non-Polymers*Number of molecules3
Total formula weight582.7
All*Total formula weight68904.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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