7PUV
Crystal structure of carbonic anhydrase XII with methyl 2-(benzenesulfonyl)-4-chloro-5-sulfamoylbenzoate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Carbonic anhydrase 12 | polymer | 263 | 29917.3 | 4 | UniProt (O43570) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase XII,Carbonic anhydrase XII,CA-XII,Tumor antigen HOM-RCC-3.1.3 |
| 2 | E, I, M, R (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, G, J, N, O... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | H, L, Q, T (A, B, C, D) | methyl 4-chloranyl-2-(phenylsulfonyl)-5-sulfamoyl-benzoate | non-polymer | 389.8 | 4 | Chemie (84Z) | |||
| 5 | K (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 1143 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 263 (UniProt: O43570)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 119669.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2361.6 | |
| All* | Total formula weight | 122030.8 |
