7PT3
Actinobacterial 2-hydroxyacyl-CoA lyase (AcHACL) mutant E493A structure in complex with substrate 2-HIB-CoA and inactive cofactor 3-deaza-ThDP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 2-hydroxyacyl-CoA lyase | polymer | 612 | 65304.1 | 2 | Pfam (PF02776) Pfam (PF00205) Pfam (PF02775) UniProt (by SIFTS) (P0DUV9) In PDB | Actinomycetospora chiangmaiensis DSM 45062 | |
2 | A, B | 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE | non-polymer | 423.3 | 2 | Chemie (TPW) | |||
3 | A, B | S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} 2-hydroxy-2-methylpropanethioate | non-polymer | 853.6 | 2 | Chemie (3KK) | |||
4 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
5 | water | water | 18.0 | 969 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 130608.2 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 2626.8 | |
All* | Total formula weight | 133235.0 |