7PS1
Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-27 Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E | Spike protein S1 | polymer | 210 | 23646.6 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 | |
2 | A | Beta-27 Fab heavy chain | polymer | 222 | 23532.5 | 1 | Homo sapiens (Human) | ||
3 | B | Beta-27 Fab light chain | polymer | 214 | 23129.5 | 1 | Homo sapiens (Human) | ||
4 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
5 | E, A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
6 | E, A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
7 | A, B | IODIDE ION | non-polymer | 126.9 | 4 | Chemie (IOD) | |||
8 | B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
9 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
E: 333 - 526 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Met 319 | - | initiating methionine |
Gly 320 | - | expression tag |
Cys 321 | - | expression tag |
Val 322 | - | expression tag |
Ala 323 | - | expression tag |
Glu 324 | - | expression tag |
Thr 325 | - | expression tag |
Gly 326 | - | expression tag |
His 327 | - | expression tag |
His 328 | - | expression tag |
His 329 | - | expression tag |
His 330 | - | expression tag |
His 331 | - | expression tag |
His 332 | - | expression tag |
Asn 417 | Lys 417 | variant |
Lys 484 | Glu 484 | variant |
Tyr 501 | Asn 501 | variant |
Lys 527 | - | expression tag |
Lys 528 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 70308.6 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 1451.3 | |
All* | Total formula weight | 71759.8 |