7PRX
wildtype ligand binding domain of the glucocorticoid receptor complexed with velsecorat and a PGC1a coactivator fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glucocorticoid receptor | polymer | 250 | 29108.9 | 1 | UniProt (P04150) Pfam (PF00104) In PDB | Homo sapiens (Human) | GR,Nuclear receptor subfamily 3 group C member 1 |
| 2 | B | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | polymer | 21 | 2261.6 | 1 | UniProt (Q9UBK2) In PDB | Homo sapiens | PGC-1-alpha,PPAR-gamma coactivator 1-alpha,PPARGC-1-alpha,Ligand effect modulator 6, PGC1a coactivator fragment |
| 3 | A | Velsecorat | non-polymer | 606.6 | 1 | Chemie (82H) | |||
| 4 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A: 529 - 777 (UniProt: P04150)
| PDB | External Database | Details |
|---|---|---|
| Gly 528 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31370.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 606.6 | |
| All* | Total formula weight | 31977.1 |
