7PRS

Crystal Structure of the B subunit of heat labile enterotoxin LT-IIc from Escherichia coli in complex with Sialyl-lacto-N-neotetraose d

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (DDD, EEE, FFF, GGG, HHH...)	Heat-labile enterotoxin IIA, B chain	polymer	104	11500.0	10	UniProt (H6W8F2) Pfam (PF06453)	Escherichia coli	Heat-labile enterotoxin IIc B chain,Heat-labile enterotoxin type II B subunit
2	K (DaD)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose	branched		998.9	1	In PDB
3	L, N (GaG, JaJ)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose	branched		836.7	2	In PDB GlyTouCan (G69440RD)
4	M (HaH)	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		674.6	1	In PDB GlyTouCan (G00065MO)
5	O, P, Q, R (DDD, EEE, FFF, HHH)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
6	S, T, U, V (III, JJJ, KKK, LLL)	N-acetyl-alpha-neuraminic acid	non-polymer		309.3	4	Chemie (SIA)
7	AA, BA, CA, DA, EA... (HHH, III, JJJ, KKK, LLL...)	water	water		18.0	616	Chemie (HOH)

Sequence modifications

DDD, EEE, FFF, GGG, HHH, III, JJJ, KKK, LLL, MMM: 1 - 98 (UniProt: H6W8F2)

PDB	External Database	Details
His 99	-	expression tag
His 100	-	expression tag
His 101	-	expression tag
His 102	-	expression tag
His 103	-	expression tag
His 104	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	115000.0
Branched	Number of molecules	4
	Total formula weight	3347.0
Non-Polymers*	Number of molecules	8
	Total formula weight	1621.3
All*	Total formula weight	119968.3

*Water molecules are not included.