7PR0

Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FD-5D Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G (E, A, D)	Spike protein S1	polymer	205	23150.9	3	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
2	B, E, H (L, B, F)	FD-5D Fab light chain	polymer	221	24189.9	3		Homo sapiens (Human)
3	C, F, I (H, C, G)	FD-5D Fab heavy chain	polymer	234	24536.4	3		Homo sapiens (Human)
4	J, R, U (E, A, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	K, M, P (E, L, H)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
6	L, O, T (L, H, C)	NITRATE ION	non-polymer		62.0	3	Chemie (NO3)
7	N, Q, W (L, H, G)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
8	S, V (B, F)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)

Sequence modifications

E, A, D: 333 - 526 (UniProt: P0DTC2)

PDB	External Database	Details
Glu 324	-	expression tag
Thr 325	-	expression tag
Gly 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
Lys 527	-	expression tag
Lys 528	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	215631.7
Non-Polymers*	Number of molecules	14
	Total formula weight	1428.4
All*	Total formula weight	217060.0

*Water molecules are not included.