7PR0

Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FD-5D Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	E, A, D	Spike protein S1	polymer	205	23150.9	3	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
2	L, B, F	FD-5D Fab light chain	polymer	221	24189.9	3		Homo sapiens (Human)
3	H, C, G	FD-5D Fab heavy chain	polymer	234	24536.4	3		Homo sapiens (Human)
4	E, A, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	E, L, H	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
6	L, H, C	NITRATE ION	non-polymer		62.0	3	Chemie (NO3)
7	L, H, G	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
8	B, F	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)

Sequence modifications

E, A, D: 333 - 526 (UniProt: P0DTC2)

PDB	External Database	Details
Glu 324	-	expression tag
Thr 325	-	expression tag
Gly 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
Lys 527	-	expression tag
Lys 528	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	215631.7
Non-Polymers*	Number of molecules	14
	Total formula weight	1428.4
All*	Total formula weight	217060.0

*Water molecules are not included.