7PQZ
Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A and FD-11A Fabs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | E | Spike protein S1 | polymer | 205 | 23150.9 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 2 | H | FI-3A Fab heavy chain | polymer | 222 | 23521.4 | 1 | Homo sapiens (Human) | ||
| 3 | L | FI-3A Fab light chain | polymer | 214 | 23364.8 | 1 | Homo sapiens (Human) | ||
| 4 | A | FD-11A Fab heavy chain | polymer | 232 | 25032.1 | 1 | Homo sapiens (Human) | ||
| 5 | B | FD-11A Fab light chain | polymer | 219 | 23024.4 | 1 | Homo sapiens (Human) | ||
| 6 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | E | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) |
Sequence modifications
E: 333 - 526 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Glu 324 | - | expression tag |
| Thr 325 | - | expression tag |
| Gly 326 | - | expression tag |
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| Lys 527 | - | expression tag |
| Lys 528 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 118093.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 189.9 | |
| All* | Total formula weight | 118708.0 |
