7PQY

Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (E, A)	Spike protein S1	polymer	205	23150.9	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
2	C, E (H, B)	FI-3A Fab heavy chain	polymer	222	23521.4	2		Homo sapiens (Human)
3	D, F (L, C)	FI-3A Fab light chain	polymer	214	23364.8	2		Homo sapiens (Human)
4	G (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)

Sequence modifications

E, A: 333 - 526 (UniProt: P0DTC2)

PDB	External Database	Details
Glu 324	-	expression tag
Thr 325	-	expression tag
Gly 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
Lys 527	-	expression tag
Lys 528	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	140074.3
Branched	Number of molecules	1
	Total formula weight	570.5
All*	Total formula weight	140644.9

*Water molecules are not included.