7PQU
Ligand-bound human Kv3.1 cryo-EM structure (Lu AG00563)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Potassium voltage-gated channel subfamily C member 1 | polymer | 519 | 58883.2 | 4 | UniProt (P48547) Pfam (PF02214) Pfam (PF00520) Pfam (PF07885) In PDB | Homo sapiens (human) | NGK2,Voltage-gated potassium channel subunit Kv3.1,Voltage-gated potassium channel subunit Kv4 |
2 | A, B, C, D | 1-(4-methylphenyl)sulfonyl-N-(1,3-oxazol-2-ylmethyl)pyrrole-3-carboxamide | non-polymer | 345.4 | 4 | Chemie (805) | |||
3 | A | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
4 | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 511 (UniProt: P48547)
PDB | External Database | Details |
---|---|---|
Gly 512 | - | expression tag |
Ser 513 | - | expression tag |
Leu 514 | - | expression tag |
Glu 515 | - | expression tag |
Val 516 | - | expression tag |
Leu 517 | - | expression tag |
Phe 518 | - | expression tag |
Gln 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 235532.7 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1537.9 | |
All* | Total formula weight | 237070.6 |