7PQU
Ligand-bound human Kv3.1 cryo-EM structure (Lu AG00563)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Potassium voltage-gated channel subfamily C member 1 | polymer | 519 | 58883.2 | 4 | UniProt (P48547) Pfam (PF02214) Pfam (PF00520) Pfam (PF07885) | Homo sapiens (human) | NGK2,Voltage-gated potassium channel subunit Kv3.1,Voltage-gated potassium channel subunit Kv4 |
| 2 | E, J, K, L (A, B, C, D) | 1-(4-methylphenyl)sulfonyl-N-(1,3-oxazol-2-ylmethyl)pyrrole-3-carboxamide | non-polymer | 345.4 | 4 | Chemie (805) | |||
| 3 | F, G, H, I (A) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 511 (UniProt: P48547)
| PDB | External Database | Details |
|---|---|---|
| Gly 512 | - | expression tag |
| Ser 513 | - | expression tag |
| Leu 514 | - | expression tag |
| Glu 515 | - | expression tag |
| Val 516 | - | expression tag |
| Leu 517 | - | expression tag |
| Phe 518 | - | expression tag |
| Gln 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 235532.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1537.9 | |
| All* | Total formula weight | 237070.6 |
