Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7PQQ

Structure of thermostabilised human NTCP in complex with Megabody 91

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sodium/bile acid cotransporterpolymer33336652.41UniProt (Q14973)
Pfam (PF01758)
Homo sapiens (human)Cell growth-inhibiting gene 29 protein,Na(+)/bile acid cotransporter,Na(+)/taurocholate transport protein,Sodium/taurocholate cotransporting polypeptide,Solute carrier family 10 member 1, NTCP
2B
(B)
Anti-RON nanobody,Megabody 91,Glucosidase YgjKpolymer906101583.01UniProt (P42592)
Pfam (PF21152)
Pfam (PF22422)
Lama glama (llama)Megabody 91
Sequence modifications
A: 3 - 328 (UniProt: Q14973)
PDBExternal DatabaseDetails
Met 2-initiating methionine
Thr 5Asn 5engineered mutation
Thr 11Asn 11engineered mutation
Val 33Phe 33engineered mutation
Ile 37Phe 37engineered mutation
Asn 86Lys 86engineered mutation
Ile 95Val 95engineered mutation
Ile 107Val 107engineered mutation
Leu 129Cys 129engineered mutation
His 221Leu 221engineered mutation
Leu 329-expression tag
Glu 330-expression tag
Val 331-expression tag
Leu 332-expression tag
Phe 333-expression tag
Gln 334-expression tag
B: 1 - 12 (PDB: 7PQQ)
B: 13 - 187 (UniProt: P42592)
B: 188 - 906 (PDB: 7PQQ)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight138235.4
All*Total formula weight138235.4
*Water molecules are not included.

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon