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7PQP

tau-microtubule structural ensemble based on CryoEM data

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G, I...
(A, C, E, G, I...)
Tubulin beta chainpolymer44549907.87UniProt (P02554)
Pfam (PF00091)
Pfam (PF03953)
Sus scrofa (Pig)Beta-tubulin
2B, D, F, H, J...
(B, D, F, H, J...)
Tubulin alpha-1B chainpolymer45150204.47UniProt (Q2XVP4)
Pfam (PF00091)
Pfam (PF03953)
Sus scrofa (Pig)Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
3O
(O)
Isoform Tau-F of Microtubule-associated protein taupolymer19420740.91UniProt (P10636)
Pfam (PF00418)
Homo sapiens (Human)Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau
4BA, EA, HA, P, S...
(I, K, M, A, C...)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.27Chemie (GDP)
5CA, FA, IA, Q, T...
(J, L, N, B, D...)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.27Chemie (GTP)
6AA, DA, GA, JA, R...
(H, J, L, N, B...)
MAGNESIUM IONnon-polymer24.37Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains15
Total formula weight721526.4
Non-Polymers*Number of molecules21
Total formula weight6934.8
All*Total formula weight728461.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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