7PQP
tau-microtubule structural ensemble based on CryoEM data
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G, I... | Tubulin beta chain | polymer | 445 | 49907.8 | 7 | UniProt (P02554) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (Pig) | Beta-tubulin |
2 | B, D, F, H, J... | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 7 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (Pig) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
3 | O | Isoform Tau-F of Microtubule-associated protein tau | polymer | 194 | 20740.9 | 1 | UniProt (P10636) Pfam (PF00418) In PDB | Homo sapiens (Human) | Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau |
4 | I, K, M, A, C... | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 7 | Chemie (GDP) | |||
5 | J, L, N, B, D... | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 7 | Chemie (GTP) | |||
6 | H, J, L, N, B... | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 15 |
Total formula weight | 721526.4 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 6934.8 | |
All* | Total formula weight | 728461.2 |