7PPQ
CARM1 in complex with EML736
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Histone-arginine methyltransferase CARM1 | polymer | 361 | 40850.5 | 4 | UniProt (Q9WVG6) Pfam (PF06325) In PDB | Mus musculus (Mouse) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
| 2 | A, B, C, D | methyl 6-[5-[[~{N}-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]carbamimidoyl]amino]pentylcarbamoylamino]-4-oxidanyl-naphthalene-2-carboxylate | non-polymer | 636.7 | 4 | Chemie (LSK) | |||
| 3 | A, B, C, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 614 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 130 - 487 (UniProt: Q9WVG6)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 163401.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2981.1 | |
| All* | Total formula weight | 166382.9 |
