7PP9
Three dimensional structure of human carbonic anhydrase XII in complex with sulfonamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Carbonic anhydrase 12 | polymer | 263 | 29857.2 | 4 | UniProt (O43570) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase XII,Carbonic anhydrase XII,CA-XII,Tumor antigen HOM-RCC-3.1.3 |
2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | A, B, C, D | methyl 2-chloranyl-4-cyclohexylsulfanyl-5-sulfamoyl-benzoate | non-polymer | 363.9 | 4 | Chemie (7VZ) | |||
4 | water | water | 18.0 | 734 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 3 - 262 (UniProt: O43570)
PDB | External Database | Details |
---|---|---|
Ala 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 119428.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1717.2 | |
All* | Total formula weight | 121146.0 |