7POR
PI3 kinase delta in complex with N-[2-(2-fluoro-4-{[4-(propan-2-yl)piperazin-1-yl]methyl}phenyl)pyridin-4-yl]-2-methoxy-5-(morpholin-4-yl)pyridine-3-sulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | polymer | 940 | 107823.7 | 1 | UniProt (O35904) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) | Mus musculus (Mouse) | PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,p110delta |
| 2 | B (A) | ~{N}-[2-[2-fluoranyl-4-[(4-propan-2-ylpiperazin-1-yl)methyl]phenyl]pyridin-4-yl]-2-methoxy-5-morpholin-4-yl-pyridine-3-sulfonamide | non-polymer | 584.7 | 1 | Chemie (7XH) | |||
| 3 | C (A) | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A: 106 - 1044 (UniProt: O35904)
| PDB | External Database | Details |
|---|---|---|
| Gly 105 | - | expression tag |
| Gln 508 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 107823.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 584.7 | |
| All* | Total formula weight | 108408.4 |
