7PNS
Protein kinase A catalytic subunit in complex with PKI5-24 and EN081
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 353 | 41193.7 | 1 | UniProt (P25321) Pfam (PF00069) In PDB | Cricetulus griseus (Chinese hamster) | PKA C-alpha |
2 | B | cAMP-dependent protein kinase inhibitor alpha | polymer | 20 | 2226.4 | 1 | UniProt (P63248) In PDB | Mus musculus | PKI-alpha,cAMP-dependent protein kinase inhibitor,muscle/brain isoform |
3 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
4 | A | 2-azanyl-6-[5-[(dimethylamino)methyl]-2-fluoranyl-phenyl]-1H-indole-3-carbonitrile | non-polymer | 308.4 | 1 | Chemie (7W8) | |||
5 | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A: 0 - 350 (UniProt: P25321)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 43420.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 426.5 | |
All* | Total formula weight | 43846.7 |