7PNM
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 46C12 antibody Fab fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, B, C) | Spike glycoprotein | polymer | 1322 | 146738.7 | 3 | UniProt (Q696P8) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (P36334) | Human coronavirus OC43 (HCoV-OC43) | S glycoprotein,E2,Peplomer protein |
| 2 | B, E, H (L, D, E) | 46C12 antibody light chain | polymer | 112 | 12076.6 | 3 | Homo sapiens | ||
| 3 | C, F, I (H, G, I) | 46C12 antibody heavy chain | polymer | 121 | 13606.1 | 3 | Homo sapiens (Human) | ||
| 4 | J, K, L, M, N... (F, J, K, M, N...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 5 | AA, BA, CA, DA, EA... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 24 | Chemie (NAG) |
Sequence modifications
A, B, C: 14 - 1265 (UniProt: Q696P8)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | initiating methionine |
| Pro -8 | - | expression tag |
| Met -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Gln -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Thr 1 | - | expression tag |
| Leu 2 | - | expression tag |
| Tyr 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Gly 6 | - | expression tag |
| Met 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Val 9 | - | expression tag |
| Ala 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Val 12 | - | expression tag |
| Leu 13 | - | expression tag |
| Leu 1266 | - | expression tag |
| Ile 1267 | - | expression tag |
| Lys 1268 | - | expression tag |
| Arg 1269 | - | expression tag |
| Met 1270 | - | expression tag |
| Lys 1271 | - | expression tag |
| Gln 1272 | - | expression tag |
| Ile 1273 | - | expression tag |
| Glu 1274 | - | expression tag |
| Asp 1275 | - | expression tag |
| Lys 1276 | - | expression tag |
| Ile 1277 | - | expression tag |
| Glu 1278 | - | expression tag |
| Glu 1279 | - | expression tag |
| Ile 1280 | - | expression tag |
| Glu 1281 | - | expression tag |
| Ser 1282 | - | expression tag |
| Lys 1283 | - | expression tag |
| Gln 1284 | - | expression tag |
| Lys 1285 | - | expression tag |
| Lys 1286 | - | expression tag |
| Ile 1287 | - | expression tag |
| Glu 1288 | - | expression tag |
| Asn 1289 | - | expression tag |
| Glu 1290 | - | expression tag |
| Ile 1291 | - | expression tag |
| Ala 1292 | - | expression tag |
| Arg 1293 | - | expression tag |
| Ile 1294 | - | expression tag |
| Lys 1295 | - | expression tag |
| Lys 1296 | - | expression tag |
| Ile 1297 | - | expression tag |
| Lys 1298 | - | expression tag |
| Leu 1299 | - | expression tag |
| Val 1300 | - | expression tag |
| Pro 1301 | - | expression tag |
| Arg 1302 | - | expression tag |
| Gly 1303 | - | expression tag |
| Ser 1304 | - | expression tag |
| Leu 1305 | - | expression tag |
| Glu 1306 | - | expression tag |
| Trp 1307 | - | expression tag |
| Ser 1308 | - | expression tag |
| His 1309 | - | expression tag |
| Pro 1310 | - | expression tag |
| Gln 1311 | - | expression tag |
| Phe 1312 | - | expression tag |
| Glu 1313 | - | expression tag |
| Lys 1314 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 517264.3 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 5092.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5309.0 | |
| All* | Total formula weight | 527666.1 |
