7PM8
Cryo-EM structure of the actomyosin-V complex in the strong-ADP state (central 1er, class 3)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | Phalloidin | polymer | 7 | 808.9 | 1 | BIRD (PRD_002366) | Amanita phalloides | |
2 | A | Unconventional myosin-Va | polymer | 792 | 91364.0 | 1 | UniProt (Q02440) Pfam (PF00063) Pfam (PF00612) In PDB | Gallus gallus (Chicken) | Dilute myosin heavy chain,non-muscle,Myosin heavy chain p190,Myosin-V |
3 | B | Myosin light chain 6B | polymer | 151 | 17090.3 | 1 | UniProt (P14649) In PDB | Homo sapiens (Human) | Myosin light chain 1 slow-twitch muscle A isoform,MLC1sa,Smooth muscle and nonmuscle myosin light chain alkali 6B |
4 | C | Actin, alpha skeletal muscle | polymer | 377 | 42110.0 | 1 | UniProt (P68135) Pfam (PF00022) In PDB | Oryctolagus cuniculus (Rabbit) | Alpha-actin-1 |
5 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | A, C | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) |
Sequence modifications
B: 2 - 151 (UniProt: P14649)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 151373.1 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 903.0 | |
All* | Total formula weight | 152276.1 |