7PM6
Cryo-EM structure of the actomyosin-V complex in the strong-ADP state (central 3er/2er)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (B, E) | Myosin light chain 6B | polymer | 151 | 17090.3 | 2 | UniProt (P14649) | Homo sapiens (Human) | Myosin light chain 1 slow-twitch muscle A isoform,MLC1sa,Smooth muscle and nonmuscle myosin light chain alkali 6B |
| 2 | B, F (A, D) | Unconventional myosin-Va | polymer | 792 | 91364.0 | 2 | UniProt (Q02440) Pfam (PF00063) Pfam (PF00612) | Gallus gallus (Chicken) | Dilute myosin heavy chain,non-muscle,Myosin heavy chain p190,Myosin-V |
| 3 | C, G, I (C, F, G) | Actin, alpha skeletal muscle | polymer | 377 | 42110.0 | 3 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (Rabbit) | Alpha-actin-1 |
| 4 | D, H, J (H, I, J) | Phalloidin | polymer | 7 | 808.9 | 3 | BIRD (PRD_002366) | Amanita phalloides | |
| 5 | K, N, O, R, T (A, C, D, F, G) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 6 | L, M, P, Q, S (A, C, D, F, G) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 5 | Chemie (ADP) |
Sequence modifications
B, E: 2 - 151 (UniProt: P14649)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 345665.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2257.5 | |
| All* | Total formula weight | 347922.6 |
