7PLZ
Cryo-EM structure of the actomyosin-V complex in the rigor state (central 3er/2er, young JASP-stabilized F-actin)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Unconventional myosin-Va | polymer | 792 | 91364.0 | 2 | UniProt (Q02440) Pfam (PF00063) Pfam (PF00612) | Gallus gallus (Chicken) | Dilute myosin heavy chain,non-muscle,Myosin heavy chain p190,Myosin-V |
| 2 | B, E, G (C, F, G) | Actin, alpha skeletal muscle | polymer | 377 | 42110.0 | 3 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (Rabbit) | Alpha-actin-1 |
| 3 | C, F (B, E) | Myosin light chain 6B | polymer | 151 | 17090.3 | 2 | UniProt (P14649) | Homo sapiens (Human) | Myosin light chain 1 slow-twitch muscle A isoform,MLC1sa,Smooth muscle and nonmuscle myosin light chain alkali 6B |
| 4 | H, M, Q (C, F, G) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 5 | I, N, R (C, F, G) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 6 | J, O, S (C, F, G) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 7 | K, L, P (C, G) | Jasplakinolide | non-polymer | 709.7 | 3 | Chemie (9UE) |
Sequence modifications
B, E: 2 - 151 (UniProt: P14649)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 343238.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3768.4 | |
| All* | Total formula weight | 347006.8 |
