7PLR
Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (AAA, BBB, DDD, GGG) | RNA-directed RNA polymerase L | polymer | 184 | 21722.6 | 4 | UniProt (A5HC98) Pfam (PF15518) | Bunyavirus La Crosse | Protein L,Large structural protein,Replicase,Transcriptase |
| 2 | E, O, S (AAA, DDD, GGG) | Baloxavir acid | non-polymer | 483.5 | 3 | Chemie (E4Z) | |||
| 3 | F, H, P, T (AAA, DDD, GGG) | FORMIC ACID | non-polymer | 46.0 | 4 | Chemie (FMT) | |||
| 4 | G (AAA) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | I, J, K, L, M... (AAA, BBB, DDD, GGG) | MANGANESE (II) ION | non-polymer | 54.9 | 10 | Chemie (MN) | |||
| 6 | W, X, Y, Z (AAA, BBB, DDD, GGG) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
AAA, BBB, DDD, GGG: 1 - 183 (UniProt: A5HC98)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 86890.4 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2276.0 | |
| All* | Total formula weight | 89166.5 |
