7PJE
Inhibiting parasite proliferation using a rationally designed anti-tubulin agent
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, C) | Tubulin alpha chain | polymer | 449 | 49639.0 | 2 | UniProt (P41351) | Tetrahymena thermophila | Alpha-tubulin |
| 2 | B, E (B, D) | Tubulin beta chain | polymer | 443 | 49617.7 | 2 | UniProt (P41352) | Tetrahymena thermophila | Beta-tubulin |
| 3 | C, F (F, E) | Darpin D1 | polymer | 155 | 16435.6 | 2 | synthetic construct | ||
| 4 | G, I, L, M (A, B, C, D) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) | |||
| 5 | H, J, K (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 6 | N, O, P, Q, R... (A, B, F, C, D...) | water | water | 18.0 | 1053 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 231384.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2165.6 | |
| All* | Total formula weight | 233550.3 |
