7PJE

Inhibiting parasite proliferation using a rationally designed anti-tubulin agent

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Tubulin alpha chain	polymer	449	49639.0	2	UniProt (P41351) Pfam (PF00091) Pfam (PF03953) In PDB	Tetrahymena thermophila	Alpha-tubulin
2	B, D	Tubulin beta chain	polymer	443	49617.7	2	UniProt (P41352) Pfam (PF00091) Pfam (PF03953) In PDB	Tetrahymena thermophila	Beta-tubulin
3	F, E	Darpin D1	polymer	155	16435.6	2		synthetic construct
4	A, B, C, D	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	4	Chemie (GTP)
5	A, B, C	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
6		water	water		18.0	1053	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	231384.7
Non-Polymers*	Number of molecules	7
	Total formula weight	2165.6
All*	Total formula weight	233550.3

*Water molecules are not included.