7PJE
Inhibiting parasite proliferation using a rationally designed anti-tubulin agent
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, C) | Tubulin alpha chain | polymer | 449 | 49639.0 | 2 | UniProt (P41351) | Tetrahymena thermophila | Alpha-tubulin |
| 2 | B, E (B, D) | Tubulin beta chain | polymer | 443 | 49617.7 | 2 | UniProt (P41352) | Tetrahymena thermophila | Beta-tubulin |
| 3 | C, F (F, E) | Darpin D1 | polymer | 155 | 16435.6 | 2 | synthetic construct | ||
| 4 | G, I, L, M (A, B, C, D) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | H, J, K (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) PubChem (888) | |||
| 6 | N, O, P, Q, R... (A, B, F, C, D...) | water | water | 18.0 | 1053 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 231384.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2165.6 | |
| All* | Total formula weight | 233550.3 |
