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7PII

Structure of the human CCAN CENP-A alpha-satellite complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Histone H3-like centromeric protein Apolymer14016023.62UniProt (P49450)
Pfam (PF00125)
Homo sapiens (Human)Centromere autoantigen A,Centromere protein A,CENP-A
2B, F
(B, F)
Histone H4polymer10311394.42UniProt (P62805)
Pfam (PF15511)
Homo sapiens (Human)
3C, G
(C, G)
Histone H2A type 1-Cpolymer15316666.32UniProt (Q93077)
Pfam (PF00125)
Pfam (PF16211)
Homo sapiens (Human)H2A-clustered histone 6,Histone H2A/l
4D, H
(D, H)
Histone H2B type 1-C/E/F/G/Ipolymer12613937.22UniProt (P62807)
Pfam (PF00125)
Homo sapiens (Human)Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l
5I
(I)
DNA (122-MER)polymer17152747.81Homo sapiens
6J
(J)
DNA (123-MER)polymer17152800.81Homo sapiens
7K, L
(K, L)
Centromere protein Cpolymer54561943.12UniProt (Q03188)
Pfam (PF15622)
Pfam (PF15620)
Homo sapiens (Human)CENP-C,Centromere autoantigen C,Centromere protein C 1,CENP-C 1,Interphase centromere complex protein 7
Sequence modifications
C, G: 0 - 129 (UniProt: Q93077)
PDBExternal DatabaseDetails
Met -23-initiating methionine
Gly -22-expression tag
Ser -21-expression tag
Ser -20-expression tag
His -19-expression tag
His -18-expression tag
His -17-expression tag
His -16-expression tag
His -15-expression tag
His -14-expression tag
Ser -13-expression tag
Pro -12-expression tag
Gly -11-expression tag
Leu -10-expression tag
Glu -9-expression tag
Val -8-expression tag
Leu -7-expression tag
Phe -6-expression tag
Gln -5-expression tag
Gly -4-expression tag
Pro -3-expression tag
Arg -2-expression tag
Gly -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight345478.0
All*Total formula weight345478.0
*Water molecules are not included.

237423

PDB entries from 2025-06-11

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