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7PIF

Protein kinase A catalytic subunit in complex with PKI5-24 and EN086

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
cAMP-dependent protein kinase catalytic subunit alphapolymer35341193.71UniProt (P25321)
Pfam (PF00069)
Cricetulus griseus (Chinese hamster)PKA C-alpha
2B
(B)
cAMP-dependent protein kinase inhibitor alphapolymer202226.41UniProt (P63248)Mus musculusPKI-alpha,cAMP-dependent protein kinase inhibitor,muscle/brain isoform
3C
(A)
5-[3-[4-(aminomethyl)oxan-4-yl]phenyl]-2-azanyl-benzenecarbonitrilenon-polymer307.41Chemie (7QL)
4D
(A)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
5E
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6F, G
(A, B)
waterwater18.0369Chemie (HOH)
Sequence modifications
A: 0 - 350 (UniProt: P25321)
PDBExternal DatabaseDetails
Gly -2-expression tag
His -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43420.2
Non-Polymers*Number of molecules3
Total formula weight461.0
All*Total formula weight43881.2
*Water molecules are not included.

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PDB entries from 2025-07-30

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