7PI3
PfCyRPA bound to Fab fragments from monoclonal antibodies Cy.003, Cy.004 and Cy.007
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, H, O, V (A, H, O, V) | Cysteine-rich protective antigen | polymer | 343 | 40184.0 | 4 | UniProt (Q8IFM8) Pfam (PF18638) | Plasmodium falciparum 3D7 | Inactive sialidase CyRPA,PfCyRPA |
| 2 | B, I, P, W (B, I, P, W) | Monoclonal antibody Cy.003 heavy chain | polymer | 230 | 23855.6 | 4 | Gallus gallus | ||
| 3 | C, J, Q, X (C, J, Q, X) | Monoclonal antibody Cy.003 light chain | polymer | 210 | 22372.6 | 4 | Gallus gallus | ||
| 4 | D, K, R, Y (D, K, R, Y) | Monoclonal antibody Cy.007 heavy chain | polymer | 230 | 24030.8 | 4 | Gallus gallus | ||
| 5 | E, L, S, Z (E, L, S, Z) | Monoclonal antibody Cy.007 light chain | polymer | 209 | 22380.5 | 4 | Gallus gallus | ||
| 6 | AA, F, M, T (F, M, T, a) | Monoclonal antibody Cy.004 heavy chain | polymer | 321 | 34168.1 | 4 | Gallus gallus | ||
| 7 | BA, G, N, U (G, N, U, b) | Monoclonal antibody Cy.004 light chain | polymer | 209 | 22451.6 | 4 | Gallus gallus | ||
| 8 | CA, DA, EA, FA, GA... (F, H, M, T, a) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) |
Sequence modifications
A, H, O, V: 29 - 362 (UniProt: Q8IFM8)
| PDB | External Database | Details |
|---|---|---|
| Ala 147 | Ser 147 | conflict |
| Ala 324 | Thr 324 | conflict |
| Ala 340 | Thr 340 | conflict |
| Gly 363 | - | expression tag |
| Gly 364 | - | expression tag |
| Gly 365 | - | expression tag |
| Gly 366 | - | expression tag |
| Ser 367 | - | expression tag |
| Glu 368 | - | expression tag |
| Pro 369 | - | expression tag |
| Glu 370 | - | expression tag |
| Ala 371 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 757773.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 320.6 | |
| All* | Total formula weight | 758093.9 |
