7PHW
PfCyRPA bound to monoclonal antibody Cy.004 Fab fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Cysteine-rich protective antigen | polymer | 343 | 40184.0 | 2 | UniProt (Q8IFM8) Pfam (PF18638) | Plasmodium falciparum (isolate 3D7) | Inactive sialidase CyRPA,PfCyRPA |
| 2 | B, E (B, E) | Monoclonal antibody Cy.004 heavy chain | polymer | 321 | 34168.1 | 2 | Gallus gallus | ||
| 3 | C, F (C, F) | Monoclonal antibody Cy.004 light chain | polymer | 209 | 22451.6 | 2 | Gallus gallus | ||
| 4 | G, H, I, J (A, B, D, E) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
A, D: 29 - 362 (UniProt: Q8IFM8)
| PDB | External Database | Details |
|---|---|---|
| Ala 147 | Ser 147 | conflict |
| Ala 324 | Thr 324 | conflict |
| Ala 340 | Thr 340 | conflict |
| Gly 363 | - | expression tag |
| Gly 364 | - | expression tag |
| Gly 365 | - | expression tag |
| Gly 366 | - | expression tag |
| Ser 367 | - | expression tag |
| Glu 368 | - | expression tag |
| Pro 369 | - | expression tag |
| Glu 370 | - | expression tag |
| Ala 371 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 193607.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 193767.9 |
