7PHP
Structure of Multidrug and Toxin Compound Extrusion (MATE) transporter NorM by NabFab-fiducial assisted cryo-EM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Multidrug resistance protein NorM | polymer | 484 | 52462.1 | 1 | UniProt (D7H904) Pfam (PF01554) UniProt (by SIFTS) (Q9KRU4) | Vibrio cholerae RC385 | Na(+)/drug antiporter |
| 2 | B (H) | NabFab HC | polymer | 239 | 25684.5 | 1 | synthetic construct | ||
| 3 | C (L) | NabFab LC | polymer | 215 | 23258.8 | 1 | synthetic construct | ||
| 4 | D (N) | NorM-Nb17_4 | polymer | 132 | 14357.0 | 1 | synthetic construct | ||
| 5 | E (K) | Anti-Fab nanobody | polymer | 123 | 13390.6 | 1 | Lama glama | ||
| 6 | F, G, H (H, L, N) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A: 0 - 457 (UniProt: D7H904)
| PDB | External Database | Details |
|---|---|---|
| Met -26 | - | initiating methionine |
| Gly -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Leu -11 | - | expression tag |
| Glu -10 | - | expression tag |
| Val -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Phe -7 | - | expression tag |
| Gln -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Thr -1 | - | expression tag |
| Thr 401 | Ile 405 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 129153.0 | |
| All* | Total formula weight | 129153.0 |
