7PGU
Autoinhibited structure of human neurofibromin isoform 2 stabilized by Zinc.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (F, N) | Neurofibromin | polymer | 2839 | 319757.7 | 2 | UniProt (P21359) Pfam (PF00616) Pfam (PF13716) Pfam (PF21877) | Homo sapiens (Human) | Neurofibromatosis-related protein NF-1 |
| 2 | C, E (F, N) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 720.0 | 2 | Chemie (PEV) PubChem (5326793) PubChem (9546967) PubChem (16040250) | |||
| 3 | D, F (F, N) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H (F, N) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 639515.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1570.8 | |
| All* | Total formula weight | 641086.2 |
